The Proteomic Landscape of Triple Negative Breast Cancer

This tool allows you to examine associations between genetic mutations and protein expression. Select a gene below to generate a volcano plot, then select specific proteins from the plot to display the protein abundance and gene copy number profile.

  • BUB1B
  • FAM22B
  • KIAA1549
  • MYST4
  • NF1
  • PLAG1
  • PML
  • GDS1
  • BCOR
  • MLL3
  • BCR
  • ATM
  • BRCA2
  • PIK3CA
  • TP53
Subtype clusters were determined using hierarchical clustering of proteome profiles as reported in the manuscript that accompanies this website, Lawrence et al. (2015). Cluster membership is indicated in the protein abundance profile. Copy number and mutation data was obtained from the Sanger Institute Catalogue Of Somatic Mutations In Cancer web site,  http://www.sanger.ac.uk/cosmic Bamford et al (2004).